The experiences of clinical research staff during an HIV cure trial with an analytical treatment — research event update (updated 2026-04-14T12:08)
The experiences of clinical research staff during an HIV cure trial with an analytical treatment
| Field | Value |
|---|---|
| date | 2026-04-14 |
| event_type | pubmed |
| headline | The experiences of clinical research staff during an HIV cure trial with an analytical treatment |
| research_domain | generic |
| scope | hiv-aids |
| source_meta | {"source":{"sourceId":"pubmed","name":"PubMed","tier":"T2","url":"https://pubmed.ncbi.nlm.nih.gov","documentUrl":"https://pubmed.ncbi.nlm.nih.gov/41851963/","documentTitle":"The experiences of clinical research staff during an HIV cure trial with an analytical treatment interruption in Durban, South Africa."},"hypothesisLinks":[{"hypothesisId":"hyp:hiv-aids:p180d:314567277e","direction":"supports","weight":0.286}],"flags":[],"direction":"supports","relevanceScore":0.333,"publishedAt":"2026-03-19T00:00:00.000Z","metadata":{"pmid":"41851963","journal":"HIV research & clinical practice","extractionMethod":"eutils","query":"("HIV" OR "HIV-1" OR "HIV-2" OR "human immunodeficiency virus" OR "HIV/AIDS") AND ("drug resistance" OR cluster OR outbreak OR transmission OR surveillance OR incidence OR prevalence OR recombinant OR "treatment failure")","queries":["("HIV" OR "HIV-1" OR "HIV-2" OR "human immunodeficiency virus" OR "HIV/AIDS") AND ("drug resistance" OR cluster OR outbreak OR transmission OR surveillance OR incidence OR prevalence OR recombinant OR "treatment failure")"],"scopeHints":["hiv-aids"],"language":"en","extractedTitle":"The experiences of clinical research staff during an HIV cure trial with an analytical treatment interruption in Durban, South Africa.","claimLevel":true,"literatureSource":"pubmed","claimOrdinal":0,"claimFingerprint":"4cfa0036670e4acca1fcdce6a0c17973f61a40cec5839d374eb8ba85b9c9b63e","signalClass":"surveillance","pathogens":["HIV"],"hosts":[],"places":["South Africa"],"country":"South Africa","location":"South Africa","canonicalPlaceIds":["south-africa"],"lineages":[],"mutations":[],"resistanceGenes":[],"counts":{"cases":0,"deaths":0,"samples":0},"studyType":null,"certainty":null,"classification":{"strategy":"keyword-v1","scopeId":"hiv-aids","hypothesisMatches":1,"scopeRelevance":0.333,"matchedIndicators":["hiv","HIV"]}}} |
| source_url | https://pubmed.ncbi.nlm.nih.gov/41851963/ |
| summary | The experiences of clinical research staff during an HIV cure trial with an analytical treatment interruption in Durban, South Africa.. HIV cure trials involving analytical treatment interruptions (ATIs) are expanding in resource-limited settings where HIV prevalence is highest, such as South Africa. Given the socio-economic challenges in these regions, ATI-inclusive trials may present unintended mental health risks to trial participants. |