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Epi Canary — Epidemic IntelligenceEvidence-led epidemic intelligence. Source-attributed evidence.
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Public note

For situational awareness and research transparency. Not medical advice.

Novel Pathogen Detectionactive

At least one confirmed Clade Ib case in the United States linked to the Mexico-US border corridor (distinct from the San Francisco Clade I case) within 90 days, based on Mexico's confirmed Clade Ib Jan 2026, high-volume cross-border movement, and CDC diagnostic pause creating federal detection gaps.

System-generated assessment. This assessment remains under review until the stated horizon or until sufficient evidence allows evaluation.

Moderate confidence

Confidence in this assessment
40%

The evidence is meaningful, but there is still material uncertainty. Based on 5 linked evidence items and assessed against 90D.

Assessed through 90D·5 linked evidence items·Tracking since Apr 20, 2026

02

How this assessment will be evaluated

The criteria the system uses to determine whether this assessment is borne out by the stated horizon.

Automated

Method

Evidence Match

The condition the system checks for when evaluating this assessment.

Minimum source quality

T1Primary Institutional

Evidence must meet or exceed this credibility tier to count toward evaluation.

Required terms

cross-borderhigh-volumediagnosticconfirmed

03

Evidence quality mix

Tracking since Apr 20, 2026.

T11
T24
▸Integrity referencesCryptographic hashes for verification

Registration

06

Scope synthesis

The current analyst narrative for this scope.

Open synthesis →

Africa CDC Outbreak Brief 26 confirms multi-country Africa Clade Ib burden; MPXV female genital tract replication study reinforces multi-mode transmission plausibility for Clade Ib non-sexual spread hypotheses.

No US Clade Ib case linked to Mexico corridor

07

Evidence linked to this assessment

5 linked items.

MPOX - USA (03): (CALIFORNIA) SAN FRANCISCO, CLADE I. The CDPH is monitoring the situation and e

Currently interpreted as supporting evidence for 2 tracked assessments.

T2https://www.promedmail.org/?alert=8732325neutral
Apr 19, 2026
MPOX - USA (03): (CALIFORNIA) SAN FRANCISCO, CLADE I. The California Department of Public Health

Currently interpreted as supporting evidence for 2 tracked assessments.

T2https://www.promedmail.org/?alert=8732325neutral
Apr 19, 2026
Singapore Communicable Diseases Agency (CDA) — 'Two confirmed cases of locally-transmitted mpox

Currently interpreted as supporting evidence for 7 tracked assessments.

T1https://www.cda.gov.sg/news-and-events/two-confirmed-cases-of-locally-transmitted-mpox-clade-ib-infection/supports
Apr 20, 2026
MPOX - GHANA (05): EPIDEMIC UPDATE. The Ghana Health Service has confirmed additional cases of m

Currently interpreted as supporting evidence for 12 tracked assessments.

T2https://www.promedmail.org/?alert=8732298supports
Apr 17, 2026
Singapore Communicable Diseases Agency (CDA) confirmed two cases of locally transmitted mpox Cla

Currently interpreted as supporting evidence for 8 tracked assessments.

T2https://www.cda.gov.sg/news-and-events/two-confirmed-cases-of-locally-transmitted-mpox-clade-ib-infection/supports
Apr 14, 2026

Integrity anchor

Brier 0.202

19 resolved novel pathogen detection predictions.

Mirror replication is delayed on 1 of 3 tables. Showing last replicated data.