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Epi Canary — Epidemic IntelligenceEvidence-led epidemic intelligence. Source-attributed evidence.
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Public note

For situational awareness and research transparency. Not medical advice.

Novel Pathogen Detectionactive

Pakistan Khairpur Sindh Clade Ib cluster (Apr 2026) will trigger WHO or Pakistan MoH-coordinated enhanced surveillance in Afghanistan and/or Iran within 90 days, resulting in at least one MPXV case detected in either country by July 14 2026, based on cross-border population movement patterns in the Balochistan/Sindh/Afghanistan corridor and the unprecedented pediatric severity profile indicating likely Clade Ib circulation at a regional rather than isolated scale.

System-generated assessment. This assessment remains under review until the stated horizon or until sufficient evidence allows evaluation.

Moderate confidence

Confidence in this assessment
40%

The evidence is meaningful, but there is still material uncertainty. Based on 2 linked evidence items and assessed against 90D.

Assessed through 90D·2 linked evidence items·Tracking since Apr 15, 2026

02

How this assessment will be evaluated

The criteria the system uses to determine whether this assessment is borne out by the stated horizon.

Automated

Method

Evidence Match

The condition the system checks for when evaluating this assessment.

Minimum source quality

T1Primary Institutional

Evidence must meet or exceed this credibility tier to count toward evaluation.

Required terms

moh-coordinatedunprecedentedsurveillancecross-border

03

Evidence quality mix

Tracking since Apr 15, 2026.

T22
▸Integrity referencesCryptographic hashes for verification

Registration

06

Scope synthesis

The current analyst narrative for this scope.

Open synthesis →

Clade Ib multi-modal European spread continues; new research confirms MPXV replication in vaginal/ectocervical tissue, strengthening plausibility of non-sexual transmission routes.

07

Evidence linked to this assessment

2 linked items.

9 Mpox deaths, 25 cases reported across Sindh province, Pakistan. Dunya News, April 15 2026. The

Currently interpreted as supporting evidence for 11 tracked assessments.

T2https://dunyanews.tv/en/Pakistan/mpox-sindh-deaths-casessupports
Apr 16, 2026
Pakistan Sindh Mpox Update — Apr 14 2026 (Sindh Health Department, via The Nation Pakistan, Apr

This report is recorded in the evidence trail but is not yet linked to a tracked assessment.

T2https://www.nation.com.pk/16-Apr-2026/mpox-update-25-confirmed-cases-9-deaths-reported-sindh
neutral
Apr 20, 2026

Integrity anchor

Brier 0.202

19 resolved novel pathogen detection predictions.

Mirror replication is delayed on 2 of 3 tables. Showing last replicated data. Data may be stale.